Finding high-purity acetic acid is essential for precise chemical work, including lab calibrations and chromatographic procedures. This guide highlights select acetic acid products and related reagents, focusing on purity, handling, and suitability for sensitive applications such as HPLC. The products below cover glacial acetic acid in food and ACS-grade forms, plus compatible alternatives for broader chemical work, with a practical buying guide to support informed choices.
| Product | Brand | Purity / Grade | Volume |
|---|---|---|---|
| 950ml Bottle Food Grade Glacial Acetic Acid | Duda Energy | Food Grade, 99.85+% Pure | 950 ml |
| Acetic Acid, 17.4 M Glacial | Carolina | Glacial, ACS Grade | 30 ml |
| 5 Gallon Pail Food Grade Glacial Acetic Acid | Duda Energy | Food Grade, 99.85+% Pure | 5 gal |
Note: HPLC-grade purity is typically associated with ultra-high purity solvents and standards. When selecting acetic acid for HPLC-related work, verify that the product meets stringent analytical specifications for trace impurities and moisture. The following sections present five relevant options and how they might fit varied lab needs.
950ml Bottle Food Grade Glacial Acetic Acid

Brand: Duda Energy. Features: Food Grade, 99.85+% Pure, Freezes at 62°F, May be used to make 5-20% Common Vinegar for Food Applications, Use in cooking, cleaning & More. This product offers high purity suitable for general lab prep and culinary-grade needs, with practical handling guidance for cold storage and dilution. While not explicitly labeled for analytical HPLC use, its high purity makes it a common choice for educational and routine prep work in labs that require reliable acetic acid sources.
Acetic Acid, 17.4 M Glacial ACS Grade

Brand: Carolina. Features: Formula CH3CO2H, 60.05 g/mol, CAS 64-19-7, Clear colorless liquid with strong odor; colorless solid below 16°C (61°F). Notes on storage and support are included, reflecting Carolina’s long-standing role as a science supplier. This glacial acetic acid in ACS-grade form is aligned with laboratory expectations for purity and consistent behavior in reactions, making it suitable for controlled experiments and standard preparation in chemical labs.
5 Gallon Pail Food Grade Glacial Acetic Acid

Brand: Duda Energy. Features: Food Grade, 99.85+% Pure, Freezes at 62°F, May be used to make 5-20% Common Vinegar for Food Applications, Use in cooking, cleaning & More. This large-volume option is designed for institutional settings or labs that require bulk supply of high-purity acetic acid for dilution, reagent preparation, or cleaning applications where food-grade standards are favored. Consider storage, handling equipment, and container compatibility for long-term use.
Hydrochloric Acid 31% – Technical Grade (20 BE) – 1 Quart

Brand: Alliance Chemical. Features: INDUSTRIAL STRENGTH, 31% concentration with Baumé 20; High purity for robust industrial performance; Wide-range utility for pH regulation, surface conditioning, and deep cleaning. This product is intended for professional applications requiring strong acid capabilities beyond standard laboratory prep. Exercise strict safety measures and consult material safety data sheets for handling and compatibility with lab materials and equipment.
Hydrochloric Acid 37% ACS Reagent Grade

Brand: Alliance Chemical. Features: High Concentration 37%, ACS Reagent Grade meets ACS specifications for research and laboratory uses; Essential Laboratory Reagent for a variety of reactions, titrations, and cleaning. This product is designed for precise analytical work where ACS-grade purity and label accuracy are critical. Proper storage and corrosion-resistant containers are important considerations in lab environments.
Buying Guide
When selecting acetic acid or related reagents for lab work, consider these factors to balance safety, purity, and applicability:
- Purity and grade: For analytical work and chromatographic prep, ACS-grade or reagent-grade materials with trace impurity data are preferable to standard technical or food-grade products.
- Volume and storage: Assess daily usage and storage space. Large-volume containers reduce replacement frequency but require appropriate containment to prevent spills and moisture uptake.
- Stability and handling: Acetic acid freezes near 62°F; store above this temperature or in controlled environments. Use compatible containers and PPE to minimize exposure risks.
- Intended application: Distinguish culinary, educational, and laboratory use. For HPLC or highly sensitive analyses, verify supplier specifications, lot-to-lot consistency, and any certification documentation.
- Safety and compliance: Review Safety Data Sheets (SDS), appropriate labeling, and disposal guidelines. Follow local regulations for storage, transport, and waste.
- Alternatives and flexibility: Having a mix of acetic acid grades can support different workflows—from routine prep to specialized titrations—without compromising analytical integrity.